The Shocking Truth About Allergies: How Modern Life May Be Making You Sick

Discover the surprising reason why allergies are on the rise and how modern hygiene may be triggering your body's overactive immune response. Learn the science behind allergies, their connection to parasites, and what you can do to manage them effectively.

Rebecca Hayes, PhD

2/13/20254 min read

a worm on a leaf
a worm on a leaf

The Real Reason Why You Have Allergies

Allergies are like setting off a nuclear bomb because you found a spider in your room—sure, the spider is gone, but so is everything else. While allergies might seem like your body overreacting for no good reason, there’s actually an interesting (and kind of gross) theory that explains why they happen: we got rid of worms.

What Are Allergies Really?

Allergies are your body’s way of treating harmless substances—like pollen, dust, or even peanuts—as major threats. The moment you encounter one of these allergens, your immune system launches a full-scale war, complete with sneezing, swelling, itching, and in some cases, life-threatening reactions.

What makes allergies even weirder is how unpredictable they are. You could go your entire life eating shrimp with no issues, and then one day, out of nowhere, your immune system decides that shrimp is an enemy and tries to kill you for eating it. But why does this happen? Why does our body flip the table over harmless things?

The Worm Theory: A Possible Cause of Allergies

For most of human history, parasitic worms were an unavoidable part of life. Drinking water was often contaminated, and worms would settle into human bodies, sometimes for decades. Our immune system had to come up with a way to fight them off.

Here’s the problem: worms are massive compared to bacteria or viruses. They’re tough, with protective layers that even stomach acid can’t break down. Our bodies needed a serious weapon to deal with them.

Enter IgE antibodies, the immune system’s version of a tripwire bomb. These antibodies attach to specialized immune cells called mast cells, which are packed with histamine and other chemicals. When a worm shows up, the mast cells explode, flooding the area with mucus, inflammation, and immune cells to attack and expel the invader.

This process is what happens when you have an allergic reaction. Your immune system thinks it’s under attack and launches its most powerful weapons—only now, instead of targeting worms, it’s going after cat hair or peanuts.

What Happens During an Allergic Reaction?

Let’s say you’re allergic to shrimp. When you eat it, your immune system mistakes the shrimp proteins for a dangerous invader. It releases IgE antibodies, which attach to mast cells all over your body, priming them for battle. The next time you eat shrimp, those mast cells explode, releasing histamine and other chemicals.

Here’s what happens next:

  • Your skin swells and turns red – Your blood vessels become leaky, flooding the area with fluid, which leads to hives or swelling.

  • Your nose and lungs go into overdrive – Your body floods your respiratory system with mucus, making your nose stuffy and your lungs tighten, making it hard to breathe.

  • Your digestive system revolts – If the reaction happens in your gut, you might experience nausea, cramps, and diarrhea as your body tries to flush out the ‘threat.’

  • Anaphylaxis: The worst-case scenario – In extreme cases, your body goes into full shutdown mode, dropping blood pressure to dangerous levels and closing your airways, which can be fatal without immediate medical help.

Why Did We Develop Allergies?

The worm theory suggests that because worms were so common, our immune systems evolved to be extra aggressive. But in the last century, modern sanitation, clean drinking water, and medicine have all but eliminated these parasites in developed countries. Without worms suppressing our immune response, our immune system is now overreacting to harmless substances.

Think of it like this: your immune system is a highly trained attack dog that suddenly has nothing to fight. So now, instead of guarding against real intruders, it flips out over the mailman—or in this case, pollen and peanuts.

Is Hygiene Making Allergies Worse?

It’s possible. The rise in allergies has been especially noticeable in wealthier, cleaner environments. People who grow up on farms or in less sterile conditions tend to have fewer allergies. Some scientists believe that without exposure to dirt, bacteria, and even worms, our immune systems never learn to differentiate between real threats and harmless substances.

There are also other factors at play, like changes in diet, pollution, and microbiome diversity. But one thing is clear: allergies have skyrocketed in modern societies where parasitic infections have all but disappeared.

What Can Be Done About Allergies?

While we’re not about to reintroduce worms into our bodies (because, gross), researchers are exploring ways to ‘retrain’ the immune system. Some studies suggest that controlled exposure to certain bacteria or even worm-derived proteins might help calm overactive immune responses.

For now, treatments like antihistamines, allergy shots, and avoiding triggers are the best defense against allergies. But as science continues to uncover the roots of these immune system overreactions, we may one day have a permanent solution.

A Relic of Our Evolution

Your allergies might just be a relic of an ancient battle between humans and parasites. Without worms to fight, your immune system is like a soldier without a war—so it lashes out at the wrong things. While we still don’t have all the answers, understanding the origins of allergies gives us insight into why they happen and how we might stop them in the future.

Until then, the best we can do is manage symptoms and hope that one day, science will find a way to turn off the nuclear bomb response—without bringing back the worms.